Orthomolecular medicine is the practice of combining vitamins, minerals and amino acids to attempt to optimise nutritional content and balance in the body. It is claimed to help in mood and behaviour disorders by manipulating neurotransmitters (which are composed of amino acids). Developed by Linus Pauling Ph.D in the 1960s, who was interested in the role of enzymes in brain function.
Created in the body when protein is broken down by digestion, 22 amino acids build cells, repair tissue, form antibodies, build RNA and DNA and participate in enzyme, hormonal, oxygen and muscle activity. Some amino acids are toxic to the brain.
In a specific Russian metabolic regime (‘Primavera’), amino acid combinations are given to attempt to correct imbalances and replace the function of dead cells. It is claimed to reactivate dormant cells in the brain and reactivate chemical and electrical transfer. Progressive blocks of treatment are given, sometimes in conjunction with physical and other treatments. A review of Primavera amino acid therapy can be found in the Research section of Cerebra’s website.
Day SM et al. Growth patterns in a population of children and adolescents with cerebral palsy. Developmental Medicine and Child Neurology 2007 Mar, 49(3):167-71.
Hillesund E et al. Micronutrient status in children with cerebral palsy. Acta Paediatrica 2007 Aug, 96(8):1195-8.
[NOTE: these two research studies are not specifically in orthomolecular medicine. They simply illustrate some of the issues of nutritional balance for children with cerebral palsy. See also Nutritional approaches, under Recognised approaches, for mainstream treatment of these issues.]
